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In urine, O-dealkyl and N-deethyl-O-dealkyl metabolites and glucuronides ended up predominant. Isotonitazene and metonitazene O-dealkyl metabolites ended up the exact same molecules and will also be most likely created in the metabolization of structural analogues for instance etonitazene, protonitazene, or butonitazene, whose only difference from